ncRNA name | LSD1 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Bos taurus |
Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
Methods | siRNA transfection, CHIP assay, qPCR, Western blot |
Expression pattern | associated |
Functional description | Regulation of LSD1 by LSD1-siRNA ameliorated glucose-induced decrease in H3K4 methylation at Sod2, and prevented decrease in Sod2 gene expression. |
PubMed ID | 23221071 |
Year | 2013 |
Title | Epigenetic modification of Sod2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.